JunB 抗体 (C-Term)
Quick Overview for JunB 抗体 (C-Term) (ABIN2780414)
抗原
See all JunB (JUNB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VERKRLRNRL AATKCRKRKL ERIARLEDKV KTLKAENAGL SSTAGLLREQ
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预测反应
- Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Sheep: 100%, Yeast: 91%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against JUNB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human JUNB
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anti-Jun B Proto-Oncogene (JUNB) (pSer259) antibody
JUNB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun B Proto-Oncogene (JUNB) antibodyJUNB 适用: 人 IHC, ELISA, IF 宿主: 兔 Monoclonal 5H4 unconjugated Recombinant Antibody
anti-Jun B Proto-Oncogene (JUNB) (pSer79) antibodyJUNB 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Jun B Proto-Oncogene (JUNB) (AA 1-347) antibodyJUNB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Jun B Proto-Oncogene (JUNB) (C-Term) antibodyJUNB 适用: 人, 小鼠, 大鼠, Cow, 绵羊 WB, IHC, IP, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Jun B Proto-Oncogene (JUNB) (N-Term) antibodyJUNB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Jun B Proto-Oncogene (JUNB) (pSer259) antibodyJUNB 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Jun B Proto-Oncogene (JUNB) (AA 1-240) antibodyJUNB 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Jun B Proto-Oncogene (JUNB) (AA 20-69) antibodyJUNB 适用: 人, 小鼠, 大鼠, 犬, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Jun B Proto-Oncogene (JUNB) (N-Term) antibodyJUNB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 猴, 豚鼠, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 347 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- JunB (JUNB) (Jun B Proto-Oncogene (JUNB))
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别名
- JUNB
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背景
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The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. JunB is involved in many types of human carcinoma including T-cell lymphomas, CML,primary cutaneous lymphomas. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.JunB is an important regulator of erythroid Differentiation.
Alias Symbols: AP-1
Protein Interaction Partner: BATF, FOS, RFWD2, C19orf68, USP24, TCERG1, ZNF595, PKIA, MAP2, APLP2, FOSL1, DDIT3, ATF3, BATF2, BATF3, TCL1A, FOSL2, NPM1, NEU1, SMAD4, HOXA7, BDNF, ATF4, MAPK6, UBC, TDG, SET, SAT1, MAPK9, BRCA1, SUMO2, Cebpb, EP300, SMURF1, YY1, CREBBP, SMARCA4, JDP2,
Protein Size: 347 -
分子量
- 36 kDa
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基因ID
- 3726
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NCBI登录号
- NM_002229, NP_002220
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UniProt
- P17275
抗原
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