IGHMBP2 抗体 (N-Term)
(1 reference)Quick Overview for IGHMBP2 抗体 (N-Term) (ABIN2780407)
抗原
See all IGHMBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QLLELERDAE VEERRSWQEH SSLRELQSRG VCLLKLQVSS QRTGLYGQRL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Ighmbp2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) (AA 540-720) antibody
IGHMBP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) antibodyIGHMBP2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) (AA 646-884) antibodyIGHMBP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) (N-Term) antibodyIGHMBP2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin mu Binding Protein 2 (IGHMBP2) (N-Term) antibodyIGHMBP2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 993 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 5, pp. 855-66, (2016) (PubMed).
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: "Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 5, pp. 855-66, (2016) (PubMed).
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- IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))
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别名
- Ighmbp2
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背景
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Ighmbp2 is a 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Ighmbp2 acts as a transcription regulator. Ighmbp2 is required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Ighmbp2 exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Ighmbp2 binds to the insulin II gene RIPE3B enhancer region. Ighmbp2 may be involved in translation.Ighmbp2 is a DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region.Ighmbp2 preferentially binds to the 5'-GGGCT-3' motif. Ighmbp2 interacts with tRNA-Tyr.
Alias Symbols: AEP, Catf1, RIPE3b1, Smbp-2, Smbp2, Smubp2, nmd, sma
Protein Interaction Partner: Gtf3c1, Hnrnph1, Ruvbl1, Abt1, Zbtb14, Tyr, Ighmbp2, Ruvbl2, Hspa1b, Slit3, Robo1,
Protein Size: 993 -
分子量
- 109 kDa
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基因ID
- 20589
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NCBI登录号
- NM_009212, NP_033238
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UniProt
- P40694
抗原
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