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FOXO1 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects FOXO1 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, Pig, 犬 和 Saccharomyces cerevisiae.It has been mentioned in 1 publication
产品编号 ABIN2780391
发货至: 中国
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Quick Overview for FOXO1 抗体 (N-Term) (ABIN2780391)

抗原

See all FOXO1 抗体
FOXO1 (Forkhead Box O1 (FOXO1))

适用

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人, 小鼠, 大鼠, Cow, Pig, 犬, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This FOXO1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    N-Term

    序列

    MAEAPQVVEI DPDFEPLPRP RSCTWPLPRP EFSQSNSATS SPAPSGSAAA

    预测反应

    Cow: 92%, Dog: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rat: 85%, Yeast: 85%

    产品特性

    This is a rabbit polyclonal antibody against FOXO1A. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO1A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 655 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hsu, Hu: "Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees." in: Biogerontology, Vol. 15, Issue 4, pp. 389-400, (2014) (PubMed).

  • 抗原

    FOXO1 (Forkhead Box O1 (FOXO1))

    别名

    FOXO1A

    背景

    FOXO1A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of FOXO1A has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of FOXO1A gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
    Alias Symbols: FKH1, FKHR, FOXO1A
    Protein Interaction Partner: EP300, AKT1, MST1, SIRT1, FHL2, ATG7, IRF3, FSHR, ESR1, Ubc, TXNRD1, RARA, MDM2, NLK, SKP2, SIRT2, STUB1, CREBBP, PML, LRPPRC, HOXA11, HNF4A, PARP1, DYRK1A, THRB, CSNK1G1, YWHAG, GSK3B, SMAD3, PAK1, PPARG, YWHAZ, SMAD4, AR, G6PC, SRC, CEBPB, FOXG1, HOXA10
    Protein Size: 655

    分子量

    70 kDa

    基因ID

    2308

    NCBI登录号

    NM_002015, NP_002006

    UniProt

    Q12778

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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