EGR4 抗体 (C-Term)
Quick Overview for EGR4 抗体 (C-Term) (ABIN2780389)
抗原
See all EGR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RSDHLTSHVR THTGEKPFAC DVCGRRFARS DEKKRHSKVH LKQKARAEER
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%
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产品特性
- This is a rabbit polyclonal antibody against EGR4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human EGR4
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anti-Early Growth Response 4 (EGR4) antibody
EGR4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 4 (EGR4) (AA 231-474) antibodyEGR4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 4 (EGR4) (C-Term) antibodyEGR4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 小鸡, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 4 (EGR4) antibodyEGR4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 4 (EGR4) (Internal Region) antibodyVerified EGR4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Early Growth Response 4 (EGR4) (AA 1-367) antibodyEGR4 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 4 (EGR4) antibodyEGR4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 4 (EGR4) antibodyEGR4 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 486 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EGR4 (Early Growth Response 4 (EGR4))
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别名
- EGR4
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背景
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The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
Alias Symbols: NGFIC, NGFI-C, PAT133
Protein Interaction Partner: NFATC2,
Protein Size: 486 -
分子量
- 51 kDa
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基因ID
- 1961
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NCBI登录号
- NM_001965, NP_001956
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UniProt
- Q05215
抗原
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