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EGR4 抗体 (C-Term)

The 兔 多克隆 anti-EGR4 antibody (ABIN2780389) specifically detects EGR4 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 和 斑马鱼 samples.
产品编号 ABIN2780389
发货至: 中国
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Quick Overview for EGR4 抗体 (C-Term) (ABIN2780389)

抗原

See all EGR4 抗体
EGR4 (Early Growth Response 4 (EGR4))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 15
  • 1

克隆类型

  • 16
多克隆

标记

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This EGR4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 1
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    C-Term

    序列

    RSDHLTSHVR THTGEKPFAC DVCGRRFARS DEKKRHSKVH LKQKARAEER

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

    产品特性

    This is a rabbit polyclonal antibody against EGR4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human EGR4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 486 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    EGR4 (Early Growth Response 4 (EGR4))

    别名

    EGR4

    背景

    The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
    Alias Symbols: NGFIC, NGFI-C, PAT133
    Protein Interaction Partner: NFATC2,
    Protein Size: 486

    分子量

    51 kDa

    基因ID

    1961

    NCBI登录号

    NM_001965, NP_001956

    UniProt

    Q05215
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