THRB 抗体 (N-Term)
Quick Overview for THRB 抗体 (N-Term) (ABIN2780344)
抗原
See all THRB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MTPNSMTENG LTAWDKPKHC PDREHDWKLV GMSEACLHRK SHSERRSTLK
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预测反应
- Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%
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产品特性
- This is a rabbit polyclonal antibody against THRB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human THRB
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anti-Thyroid Hormone Receptor, beta (THRB) (AA 1-169) antibody
THRB 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 1-461) antibodyTHRB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 239-457) antibodyTHRB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 37-86) antibodyTHRB 适用: 人, 大鼠, 马, 犬, 豚鼠, 兔, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 1-250) antibodyTHRB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人 WB 宿主: 小鼠 Monoclonal 2386 unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人, 小鼠, 大鼠, 马, 豚鼠, Cow WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 391-440) antibodyTHRB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人, 小鼠 WB, ELISA, IF, IP, FM 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 23-55) antibodyTHRB 适用: 人 WB 宿主: 兔 Polyclonal RB54428 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 461 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- THRB (Thyroid Hormone Receptor, beta (THRB))
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别名
- THRB
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背景
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THRB is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Defects in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several transcript variants have been observed for this gene, but the full-length nature of only one has been determined so far. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
Alias Symbols: ERBA-BETA, ERBA2, GRTH, MGC126109, MGC126110, NR1A2, THR1, THRB1, THRB2, PRTH, C-ERBA-2, C-ERBA-BETA
Protein Interaction Partner: NSD1, NCOA1, RANBP9, NCOR1, RXRA, THRB, MMS19, ADAT3, NCOA2, C1D, NCOA3, ATF2, ANP32A, SUMO1, SUMO2, ROBO4, MED21, HMGN3, EIF3I, NRIP1, RXRG, RXRB, CAMK2B, TBL1XR1, NCOR2, HDAC3, SMC1A, XRCC5, TBL1X, PRKDC, LIG3, HSPA4, GPS2, XRCC6, PARP1, LRIF1, SRC, PSM
Protein Size: 461 -
分子量
- 53 kDa
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基因ID
- 7068
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NCBI登录号
- NM_000461, NP_000452
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UniProt
- P10828
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound
抗原
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