RFX5 抗体 (C-Term)
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北京 101111
Quick Overview for RFX5 抗体 (C-Term) (ABIN2780343)
抗原
See all RFX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VIKGSRSQKE AFPLAKGEVD TAPQGNKDLK EHVLQSSLSQ EHKDPKATPP
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预测反应
- Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against RFX5. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RFX5
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anti-Regulatory Factor X 5 (RFX5) (AA 1-616) antibody
RFX5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Regulatory Factor X 5 (RFX5) (AA 367-616) antibodyRFX5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X 5 (RFX5) (Internal Region) antibodyVerified RFX5 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Regulatory Factor X 5 (RFX5) (AA 1-616) antibodyRFX5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X 5 (RFX5) (AA 516-616) antibodyRFX5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B8 unconjugated
anti-Regulatory Factor X 5 (RFX5) antibodyRFX5 适用: 人 WB, ELISA, GS, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X 5 (RFX5) antibodyRFX5 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X 5 (RFX5) (N-Term) antibodyRFX5 适用: 人, 犬, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X 5 (RFX5) (C-Term) antibodyRFX5 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X 5 (RFX5) (N-Term) antibodyRFX5 适用: 人, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 616 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RFX5 (Regulatory Factor X 5 (RFX5))
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别名
- RFX5
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背景
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RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. RFX is a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX.A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX.A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.
Alias Symbols: -
Protein Interaction Partner: UBC, MRPL53, SLIRP, SRPRB, CDV3, LSM7, RPS19, RBMS1, NDUFA7, NDUFA2, ANKRA2, RFXANK, MLLT1, HDAC4, CIITA, HDAC2, RFXAP,
Protein Size: 616 -
分子量
- 65 kDa
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基因ID
- 5993
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NCBI登录号
- NM_000449, NP_000440
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UniProt
- P48382
抗原
-
