L3MBTL1 抗体 (N-Term)
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- 抗原 See all L3MBTL1 抗体
- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
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抗原表位
- N-Term
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适用
- 人, 豚鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This L3MBTL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RRREGHGTDS EMGQGPVRES QSSDPPALQF RISEYKPLNM AGVEQPPSPE
- 预测反应
- Dog: 92%, Guinea Pig: 77%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against L3MBTL. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human L3MBTL
- Top Product
- Discover our top product L3MBTL1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 772 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
- 别名
- L3MBTL (L3MBTL1 产品)
- 背景
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L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DKFZp586P1522, FLJ41181, H-L(3)MBT, KIAA0681, L3MBTL1, dJ138B7.3, L3MBTL
Protein Interaction Partner: VCP, UBC, PCNA, MCM7, MCM6, MCM5, MCM4, MCM3, CDC45, MCM2, SETD8, TP53, HIST1H1E, L3MBTL1, ETV7, ETV6, HIST2H4A, CBX3, RB1, HIST1H1B, SETD7, CBX5,
Protein Size: 772 - 分子量
- 86 kDa
- 基因ID
- 26013
- NCBI登录号
- NM_015478, NP_056293
- UniProt
- Q9Y468
- 途径
- Chromatin Binding
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