L3MBTL1 抗体 (N-Term)
Quick Overview for L3MBTL1 抗体 (N-Term) (ABIN2780244)
抗原
See all L3MBTL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RRREGHGTDS EMGQGPVRES QSSDPPALQF RISEYKPLNM AGVEQPPSPE
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预测反应
- Dog: 92%, Guinea Pig: 77%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against L3MBTL. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human L3MBTL
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 772 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
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别名
- L3MBTL
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背景
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L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DKFZp586P1522, FLJ41181, H-L(3)MBT, KIAA0681, L3MBTL1, dJ138B7.3, L3MBTL
Protein Interaction Partner: VCP, UBC, PCNA, MCM7, MCM6, MCM5, MCM4, MCM3, CDC45, MCM2, SETD8, TP53, HIST1H1E, L3MBTL1, ETV7, ETV6, HIST2H4A, CBX3, RB1, HIST1H1B, SETD7, CBX5,
Protein Size: 772 -
分子量
- 86 kDa
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基因ID
- 26013
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NCBI登录号
- NM_015478, NP_056293
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UniProt
- Q9Y468
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途径
- Chromatin Binding
抗原
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