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MED21 抗体 (Middle Region)

This 兔 多克隆 anti-MED21 antibody specifically detects MED21 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 和 斑马鱼 samples.
产品编号 ABIN2780233
发货至: 中国
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Quick Overview for MED21 抗体 (Middle Region) (ABIN2780233)

抗原

See all MED21 抗体
MED21 (Mediator Complex Subunit 21 (MED21))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 斑马鱼

宿主

  • 17
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克隆类型

  • 18
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多克隆

标记

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This MED21 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    DSLPSEESTA ALQAASLYKL EEENHEAATC LEDVVYRGDM LLEKIQSALA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against MED21. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human MED21
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 144 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MED21 (Mediator Complex Subunit 21 (MED21))

    别名

    MED21

    背景

    MED21 belongs to the Mediator complex subunit 21 family. It is the component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    Alias Symbols: SRB7, SURB7
    Protein Interaction Partner: MAGEB4, SSC5D, ZNF655, BLOC1S6, MED21, CDK8, MED19, MED26, UBC, HTT, FBXW7, MED11, MED8, MED28, MED29, MED18, MED4, MED16, MED6, MED13, MED12, MED24, MED17, MED14, MED22, MED1, ELAVL1, VAV2, SKP1, THRA, THRB, MED10, TP53, SREBF1, ZC3H13, ZSCAN1, PCBD2, TA
    Protein Size: 144

    分子量

    15 kDa

    基因ID

    9412

    NCBI登录号

    NM_004264, NP_004255

    UniProt

    Q13503

    途径

    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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