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SSX2 抗体 (C-Term)

This anti-SSX2 antibody is a 兔 多克隆 antibody detecting SSX2 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2780224
发货至: 中国

Quick Overview for SSX2 抗体 (C-Term) (ABIN2780224)

抗原

See all SSX2 抗体
SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

适用

  • 49
  • 3
  • 2

宿主

  • 43
  • 6

克隆类型

  • 46
  • 3
多克隆

标记

  • 21
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  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This SSX2 antibody is un-conjugated

应用范围

  • 34
  • 13
  • 13
  • 10
  • 6
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term

    序列

    HRWSSQNTHN IGRFSLSTSM GAVHGTPKTI THNRDPKGGN MPGPTDCVRE

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against SSX2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human SSX2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 223 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Jung, Fischer, Imig, Kleber, Nuber, Reinshagen, Kamradt, Grobholz, Knuth, Renner, Wadle: "Yeast-based identification of prostate tumor antigens provides an effective vaccine platform." in: Anticancer research, Vol. 30, Issue 3, pp. 895-902, (2010) (PubMed).

  • 抗原

    SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

    别名

    SSX2

    背景

    SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
    Alias Symbols: HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX, SSX2B, CT5.2a
    Protein Interaction Partner: KRT40, SSX2IP, RAB3IP, SYCE1, ZMIZ2, MAGEC2, AKAP9, ZBED1, TAX1BP1, BLZF1, SUZ12, EED, SMARCA5, TLE1, SMARCA2, HDAC2, HDAC1, EZH2, ATF2, RNF2,
    Protein Size: 223

    分子量

    25 kDa

    基因ID

    6757

    NCBI登录号

    NM_003147, NP_003138
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