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G3BP1 抗体 (N-Term)

Cited in 2+ publications. This anti-G3BP1 antibody is a 兔 多克隆 antibody detecting G3BP1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, 豚鼠, Cow, 兔 和 Pig.
产品编号 ABIN2780221
发货至: 中国
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Quick Overview for G3BP1 抗体 (N-Term) (ABIN2780221)

抗原

See all G3BP1 抗体
G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

适用

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人, 小鼠, 大鼠, 犬, 马, 豚鼠, Cow, 兔, Pig

宿主

  • 96
  • 7
  • 1

克隆类型

  • 74
  • 30
多克隆

标记

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This G3BP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 27
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    • 1
    N-Term

    序列

    EVFGGFVTEP QEESEEEVEE PEERQQTPEV VPDDSGTFYD QAVVSNDMEE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against G3BP. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human G3BP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 466 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lind, Svedin, Domsgen, Kapell, Laitinen, Moll, Flodström-Tullberg: "Coxsackievirus counters the host innate immune response by blocking type III interferon expression." in: The Journal of general virology, Vol. 97, Issue 6, pp. 1-12, (2016) (PubMed).

    Schulte, Liu, Panas, Thaa, Dickson, Götte, Achour, McInerney: "Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication." in: Open biology, Vol. 6, Issue 7, (2016) (PubMed).

  • 抗原

    G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

    别名

    G3BP

    背景

    G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
    Alias Symbols: G3BP, HDH-VIII
    Protein Interaction Partner: UBC, USP10, FXR2, MDM2, RNF2, BMI1, RPS27L, EDC4, RPL35, RPL14, EIF2B3, EIF3C, PTBP1, PIN1, PA2G4, YBX1, HNRNPU, FAU, SH3RF2, TARDBP, FBXO25, RIOK2, SND1, VCAM1, env, ITGA4, IL7R, FN1, EPHA8, DTX1, PABPC1, PAXIP1, ESR1, APP, NOLC1, TPM4, LCK, CSK, KCND3,
    Protein Size: 466

    分子量

    51 kDa

    基因ID

    10146

    NCBI登录号

    NM_005754, NP_005745

    UniProt

    Q13283

    途径

    SARS-CoV-2 Protein Interactome
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