FXYD5 抗体 (N-Term)
(1 reference)Quick Overview for FXYD5 抗体 (N-Term) (ABIN2780210)
抗原
See all FXYD5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LQPTSPTPTW PADETPQPQT QTQQLEGTDG PLVTDPETHK STKAAHPTDD
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预测反应
- Human: 100%, Mouse: 100%, Yeast: 90%
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产品特性
- This is a rabbit polyclonal antibody against FXYD5. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FXYD5
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anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 22-145) antibody
FXYD5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (C-Term) antibodyVerified FXYD5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 54-103) antibodyFXYD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 66-115) antibodyFXYD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 108-157) antibodyFXYD5 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (N-Term) antibodyFXYD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 70-100), (Middle Region) antibodyFXYD5 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 71-100) antibodyFXYD5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 178 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." in: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).
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: "Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." in: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).
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- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
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别名
- FXYD5
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背景
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FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.
Alias Symbols: RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241
Protein Interaction Partner: UBC,
Protein Size: 178 -
分子量
- 20 kDa
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基因ID
- 53827
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NCBI登录号
- NM_144779, NP_659003
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UniProt
- Q96DB9
抗原
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