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Glypican 3 抗体 (Middle Region)

There is 1 publication for this product available. The 兔 多克隆 anti-Glypican 3 antibody is suitable to detect Glypican 3 in samples from 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马 和 兔. It has been validated for WB 和 IHC.
产品编号 ABIN2780199
发货至: 中国
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Quick Overview for Glypican 3 抗体 (Middle Region) (ABIN2780199)

抗原

See all Glypican 3 (GPC3) 抗体
Glypican 3 (GPC3)

适用

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人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

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克隆类型

  • 114
  • 83
  • 5
多克隆

标记

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This Glypican 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    FSTIHDSIQY VQKNAGKLTT TIGKLCAHSQ QRQYRSAYYP EDLFIDKKVL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GPC3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human GPC3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 580 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bhave, Mars, Donthamsetty, Zhang, Tan, Luo, Bowen, Michalopoulos: "Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex." in: The American journal of pathology, Vol. 183, Issue 1, pp. 153-9, (2013) (PubMed).

  • 抗原

    Glypican 3 (GPC3)

    别名

    GPC3

    背景

    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome.
    Alias Symbols: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2
    Protein Interaction Partner: UBC, WNT3A, WNT7B, IGF2, FGF2,
    Protein Size: 580

    分子量

    64 kDa

    基因ID

    2719

    NCBI登录号

    NM_004484, NP_004475

    UniProt

    P51654

    途径

    Glycosaminoglycan Metabolic Process
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