MCAF1 抗体 (Middle Region)
This anti-MCAF1 antibody is a 兔 多克隆 antibody detecting MCAF1 in WB. Suitable for Pig, 小鼠 和 大鼠.
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Quick Overview for MCAF1 抗体 (Middle Region) (ABIN2780013)
抗原
See all MCAF1 (ATF7IP) 抗体
MCAF1 (ATF7IP)
(Activating Transcription Factor 7 Interacting Protein (ATF7IP))
适用
Pig, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This MCAF1 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- Middle Region
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序列
- MSTPEGEKSE KDGKAEEEER VPAEEQPPVR NEFSRRKRSK SEDMDSVESK
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预测反应
- Mouse: 100%, Pig: 92%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against Atf7ip. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Mouse Atf7ip
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anti-Activating Transcription Factor 7 Interacting Protein (ATF7IP) (AA 553-602) antibody
ATF7IP 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 Interacting Protein (ATF7IP) (AA 525-725) antibodyATF7IP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1306 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MCAF1 (ATF7IP) (Activating Transcription Factor 7 Interacting Protein (ATF7IP))
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别名
- Atf7ip
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背景
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Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Atf7ip can both act as an activator or a repressor depending on the context. It mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Atf7ip is required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Atf7ip may have ATPase activity.
Alias Symbols: 2610204M12Rik, AM, Mcaf1
Protein Interaction Partner: Atf7, Gtf2f1, Gtf2e2, Aagab, Ccnh, Gtf2h1, Ercc3, Cdk7, C1qbp, POLR2H, POLR2G, POLR2D, POLR2C,
Protein Size: 1306 -
分子量
- 138 kDa
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基因ID
- 54343
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NCBI登录号
- NM_019426, NP_062299
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UniProt
- Q7TT18
抗原
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