FIGLA 抗体 (C-Term)
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Quick Overview for FIGLA 抗体 (C-Term) (ABIN2779982)
抗原
See all FIGLA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SSTRELLGNA TQPTSCASGL KKEEEGPWAY AGHSEPLYSY HQSTVPETRS
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预测反应
- Mouse: 100%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against Figla. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Figla
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FIGLA (Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))
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别名
- Figla
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背景
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Figla is a germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. It plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. It is essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Figla binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
Alias Symbols: bHLHc8
Protein Size: 194 -
分子量
- 21 kDa
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基因ID
- 26910
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NCBI登录号
- NM_012013, NP_036143
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UniProt
- O55208
抗原
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