FOXA3 抗体 (C-Term)
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北京 101111
Quick Overview for FOXA3 抗体 (C-Term) (ABIN2779850)
抗原
See all FOXA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Foxa3 Antibody - C-terminal region
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序列
- YNFNHPFSIN NLMSEQTSTP SKLDVGFGGY GAESGEPGVY YQSLYSRSLL
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预测反应
- Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 86%, Mouse: 100%, Pig: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Foxa3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the c terminal region of mouse Foxa3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36881-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- FOXA3 (Forkhead Box A3 (FOXA3))
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别名
- Foxa3
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背景
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Background Information: Foxa3 is a transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Foxa3 is originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Foxa3 interacts with the cis-acting regulatory regions of these genes.Foxa3 is involved in glucose homeostasis, activates GLUT2 transcription and regulation of neuronal-specific transcription. Foxa3 is also involved in regulation of spermatogenesis, required for the maintenance of the testicular germ cell population and male fertility.
Gene Name: Forkhead box A3
Alternative Symbols: Hnf3, Hnf-3, Hnf3g, Tcf3g, Hnf-3g, Tcf-3g
Protein Name: Hepatocyte nuclear factor 3-gamma
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分子量
- 37kDa
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基因ID
- 15377
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NCBI登录号
- NP_032286
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UniProt
- P35584
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途径
- Carbohydrate Homeostasis
抗原
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