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- 抗原 See all ACD 抗体
- ACD (Adrenocortical Dysplasia Homolog (ACD))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACD antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PRTSAQELCS VWEPPERHRD TSAFQYKYET PSASLHTQVQ TARLSPQLVA
- 预测反应
- Cow: 83%, Dog: 85%, Guinea Pig: 85%, Horse: 85%, Human: 85%, Mouse: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against Acd. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the c terminal region of mouse Acd
- Top Product
- Discover our top product ACD Primary Antibody
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anti-Adrenocortical Dysplasia Homolog (ACD) (AA 1-544) antibody
ACD 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8-1B6 unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) antibodyACD 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2B1 unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 21-175) antibodyACD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 1-544) antibodyACD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 1-544) antibodyACD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 328-497) antibodyACD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) antibodyACD 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 467-516) antibodyACD 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 398-447) antibodyACD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 147-342) antibodyACD 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 416 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ACD (Adrenocortical Dysplasia Homolog (ACD))
- 别名
- Acd (ACD 产品)
- 别名
- PIP1 antibody, PTOP antibody, TINT1 antibody, TPP1 antibody, ACD antibody, ACD, shelterin complex subunit and telomerase recruitment factor antibody, adrenocortical dysplasia antibody, ACD antibody, Acd antibody
- 背景
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Acd is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.Acd promotes binding of POT1 to single-stranded telomeric DNA.Acd modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomer elongation by increasing telomerase processivity.Acd plays a role in shelterin complex assembly. Acd may play an essential role in organogenesis of the developing embryo.
Alias Symbols: -
Protein Size: 416 - 分子量
- 45 kDa
- 基因ID
- 497652
- NCBI登录号
- NM_001012638, NP_001012656
- UniProt
- Q5EE38
- 途径
- Telomere Maintenance
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