SMAD6 抗体 (N-Term)
Quick Overview for SMAD6 抗体 (N-Term) (ABIN2779804)
抗原
See all SMAD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- APRDASDPLA GAALEPAGGG RSREARSRLL LLEQELKTVT YSLLKR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against SMAD6. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD6
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anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibody
SMAD6 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A6 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 261-495) antibodySMAD6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-385) antibodySMAD6 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibodySMAD6 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 137-182) antibodySMAD6 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 358-386) antibodySMAD6 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 357-386), (C-Term) antibodySMAD6 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41931 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-385) antibodySMAD6 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4C8 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 496 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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别名
- SMAD6
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背景
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SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
Alias Symbols: MADH6, MADH7, HsT17432
Protein Interaction Partner: ITCH, SMURF2, BPIFA1, NEDD4L, WWP2, WWP1, USP15, USP11, PIGR, NASP, LYZ, KPNA2, CTBP2, CTBP1, UBC, ACVR1, UBE2O, BAMBI, STAMBP, ACTR1B, TGFBR1, MYD88, SMAD1, BMPR2, BMPR1B, BMPR1A, ACVR2B, ACVR1B, SMURF1, PELI1, CUL2, ELAVL1, SMAD5, RPS6KA5, TSC22D1, MAPK
Protein Size: 496 -
分子量
- 53 kDa
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基因ID
- 4091
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NCBI登录号
- NM_005585, NP_005576
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UniProt
- O43541
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途径
- Chromatin Binding
抗原
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