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SMAD6 抗体 (C-Term)
SMAD6
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 兔
WB
宿主: 兔
Polyclonal
unconjugated
SMAD6抗体详情
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抗原
See all SMAD6 抗体
SMAD6
(SMAD, Mothers Against DPP Homolog 6 (SMAD6))
抗原表位
All epitopes for SMAD6 抗体
C-Term
适用
All reactivities for SMAD6 抗体
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 兔
宿主
All hosts for SMAD6 抗体
兔
克隆类型
All clonalities for SMAD6 抗体
多克隆
标记
All conjugates for SMAD6 抗体
This SMAD6 antibody is un-conjugated
应用范围
All applications for SMAD6 抗体
Western Blotting (WB)
序列
PDGVWAYNRG EHPIFVNSPT LDAPGGRALV VRKVPPGYSI KVFDFERSGL
预测反应
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
产品特性
This is a rabbit polyclonal antibody against Smad6. It was validated on Western Blot.
纯化方法
Affinity Purified
免疫原
The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Smad6
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Discover our top product SMAD6 Primary Antibody
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anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (N-Term) antibody
SMAD6
适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 马, 斑马鱼
WB, IHC
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeat freeze-thaw cycles.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
SMAD6目标详情
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抗原
SMAD6
(SMAD, Mothers Against DPP Homolog 6 (SMAD6))
别名
Smad6 (SMAD6 产品 )
别名
madh6 antibody, madh7 antibody, Xsmad6 antibody, hst17432 antibody, AOVD2 antibody, HsT17432 antibody, MADH6 antibody, MADH7 antibody, Madh6 antibody, b2b390Clo antibody, Smad6-like antibody, smad6 antibody, wu:fb22g05 antibody, SMAD family member 6 antibody, SMAD family member 6a antibody, smad6 antibody, SMAD6 antibody, Smad6 antibody, smad6a antibody
背景
Smad6 binds to regulatory elements in target promoter regions. It may block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. It acts as a mediator of TGF-beta and BMP antiflammatory activity. It suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. Protein Interaction Partner: Smurf1, Tbx6, Bmpr2, Bmpr1a, Acvr1, Runx2, tob1a, Axin1, SMURF2, BMPR1B, Protein Size: 459
分子量
54 kDa
基因ID
17130
UniProt
O35182
途径
Chromatin Binding
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