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Interleukin enhancer-binding factor 3 (ILF3) (C-Term) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 和 Pig.
产品编号 ABIN2779788
发货至: 中国

Quick Overview for Interleukin enhancer-binding factor 3 (ILF3) (C-Term) 抗体 (ABIN2779788)

抗原

See all Interleukin enhancer-binding factor 3 (ILF3) 抗体
Interleukin enhancer-binding factor 3 (ILF3)

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Pig

宿主

  • 55
  • 2
  • 1

克隆类型

  • 48
  • 11
多克隆

标记

  • 45
  • 2
  • 2
  • 2
  • 2
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  • 2
非结合性

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    QQSYNQSPYS NYGPPQGKQK GYNHGQGSYS YSNSYNSPGG GGGSDYNYES

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 86%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against ILF3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human ILF3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 894 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Interleukin enhancer-binding factor 3 (ILF3)

    别名

    ILF3

    背景

    ILF3 may facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. ILF3 can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. ILF3 can regulate protein arginine N-methyltransferase 1 activity. ILF3 may regulate transcription of the IL2 gene during T-cell activation. It can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.
    Alias Symbols: DRBF, DRBP76, MMP4, MPHOSPH4, MPP4, NF-AT-90, NF90, NFAR, NFAR-1, TCP80, CBTF, NF110, NF90a, NF90b, NFAR2, NF110b, TCP110
    Protein Interaction Partner: PLSCR1, UBC, FBXW11, RBPMS, HUWE1, MDM2, AURKA, SUMO2, SUMO3, STAU1, IVNS1ABP, LGR4, ERG, RPA3, RPA2, RPA1, EZH2, HNRNPL, SUZ12, RNF2, BMI1, EED, VHL, VEGFA, rev, FBXO6, TARDBP, CSF2, EIF2AK2, ICAM1, IGSF8, SNORD116-22, PABPC1, RNU2-4P, RNU5B-1, RNU5A-1,
    Protein Size: 894

    分子量

    95 kDa

    基因ID

    3609

    NCBI登录号

    NM_012218, NP_036350

    UniProt

    Q12906

    途径

    M Phase
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