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NCOA3 抗体 (N-Term)

This anti-NCOA3 antibody is a 兔 多克隆 antibody detecting NCOA3 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 和 兔.
产品编号 ABIN2779676
发货至: 中国

Quick Overview for NCOA3 抗体 (N-Term) (ABIN2779676)

抗原

See all NCOA3 抗体
NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔

宿主

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克隆类型

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多克隆

标记

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This NCOA3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    ILKETVRQIR QIKEQGKTIS NDDDVQKADV SSTGQGVIDK DSLGPLLLQA

    预测反应

    Cow: 79%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against NCOA3. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human NCOA3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1420 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

    别名

    NCOA3

    背景

    NCOA3 is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
    Alias Symbols: ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, MGC141848, RAC3, SRC-1, SRC3, TNRC14, TNRC16, TRAM-1, pCIP, SRC-3, bHLHe42
    Protein Interaction Partner: PSMB9, PPARG, CUL3, ARNT2, MMS19, FBXW7, SPOP, UBC, E2F1, PTEN, ESR2, ALB, NR1I2, THRB, CHUK, KANK2, ESR1, NR3C1, MYOCD, MKL1, MKL2, PSME3, UBE3A, TP53, RARA, MAPK1, PIN1, PGR, EP300, ELAVL1, MAPK14, CREBBP, CEBPD, CEBPA, TP53BP1, TFF1, PSMC5, PSMA3, PRKC
    Protein Size: 1420

    分子量

    155 kDa

    基因ID

    8202

    NCBI登录号

    NM_006534, NP_006525

    UniProt

    Q0VF45

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha
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