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NCOR1 抗体 (N-Term)

This anti-NCOR1 antibody is a 兔 多克隆 antibody detecting NCOR1 in IHC 和 WB. Suitable for 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow 和 Saccharomyces cerevisiae.
产品编号 ABIN2779671
发货至: 中国

Quick Overview for NCOR1 抗体 (N-Term) (ABIN2779671)

抗原

See all NCOR1 抗体
NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

适用

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人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This NCOR1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    NENYKALVRR NYGKRRGRNQ QIARPSQEEK VEEKEEDKAE KTEKKEEEKK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 92%, Yeast: 85%

    产品特性

    This is a rabbit polyclonal antibody against NCOR1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 2453 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

    别名

    NCOR1

    背景

    NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
    Alias Symbols: N-CoR, TRAC1, N-CoR1, hN-CoR
    Protein Interaction Partner: RARA, TP53, ESR1, PHB2, ZBTB16, THRB, THRA, CREB1, JUN, PPARG, SQSTM1, HDAC3, UBE2I, SOX2, HDAC7, HDAC5, HDAC4, UBC, SKIL, SKI, AR, SMAD4, CSNK2A1, RUNX1T1, CXADR, TBL1XR1, vif, C1D, CHUK, YWHAZ, SMARCE1, SMARCD1, SMARCA2, RBBP4, BPTF, HMGXB4, TAB2, NCOR2
    Protein Size: 2453

    分子量

    270 kDa

    基因ID

    9611

    UniProt

    Q60974

    途径

    Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
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