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REST 抗体 (Middle Region)

Cited in 1 publication. The 兔多克隆 anti-REST antibody (ABIN2779670) specifically detects REST in WB. The antibody is reactive with 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马和兔 samples.

Western Blotting (WB) image for anti-RE1-Silencing Transcription Factor (REST) (Middle Region) antibody (ABIN2779670) (REST 抗体 (Middle Region))

REST antibody - middle region validated by WB using A549 and HEK293T cells at 1: 500. (REST 抗体 (Middle Region))

Host: Rabbit Target Name: REST Sample Tissue: Human MCF7 Antibody Dilution: 1. (REST 抗体 (Middle Region))

Host: Rabbit Target Name: REST Sample Type: MCF7 Antibody Dilution: 1. (REST 抗体 (Middle Region))

Host: Rabbit Target Name: REST Sample Type: Human Fetal Liver Antibody Dilution: 1. (REST 抗体 (Middle Region))

6 images

(1 reference)

产品编号 ABIN2779670

发货至: 中国

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Quick Overview for REST 抗体 (Middle Region) (ABIN2779670)

抗原

See all REST 抗体

REST (RE1-Silencing Transcription Factor (REST))

适用

人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔

宿主

兔

克隆类型

多克隆

标记

This REST antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product REST Primary Antibody

抗原表位
8

5

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2

2

2

1

1

1

1

1

1

1

1

1

1

1
Middle Region

序列

PMLPPSAVEE REAVSKTALA SPPATMAANE SQEIDEDEGI HSHEGSDLSD

预测反应

Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

产品特性

This is a rabbit polyclonal antibody against REST. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human REST
anti-RE1-Silencing Transcription Factor (REST) (AA 401-450) antibody
REST 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-RE1-Silencing Transcription Factor (REST) antibody
REST 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-RE1-Silencing Transcription Factor (REST) antibody
REST 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB1200 unconjugated Recombinant Antibody

anti-RE1-Silencing Transcription Factor (REST) (AA 760-1060) antibody
REST 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-RE1-Silencing Transcription Factor (REST) (AA 250-350) antibody
REST 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-RE1-Silencing Transcription Factor (REST) antibody
REST 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB8545 unconjugated

anti-RE1-Silencing Transcription Factor (REST) (Internal Region) antibody
Verified REST 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-RE1-Silencing Transcription Factor (REST) (C-Term) antibody
REST 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-RE1-Silencing Transcription Factor (REST) (AA 972-1021) antibody
REST 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-RE1-Silencing Transcription Factor (REST) (AA 20-69) antibody
REST 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1097 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Mehta, Kim, Vemuganti: "Long Noncoding RNA FosDT Promotes Ischemic Brain Injury by Interacting with REST-Associated Chromatin-Modifying Proteins." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 50, pp. 16443-9, (2015) (PubMed).
抗原

REST (RE1-Silencing Transcription Factor (REST))

别名

REST

背景

REST is a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis.This gene encodes a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described, however, their full length nature has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NRSF, XBR
Protein Interaction Partner: BTRC, UBC, FBXW11, CSNK1E, NEDD8, EHMT2, EIF4A3, FBXW4, FBXW7, FBXW5, FBXW8, FBXW2, SIN3A, TERF2, GRIA2, SUB1, GTF2B, Tbp, SIN3B, HDAC1, RCOR1, SP1, SMARCE1, SMARCC2, SMARCA4, CDYL, HDAC5, HDAC4, HTT, NCOR1, KDM5C, RNF2, HDAC2, STMN2, GRM2, CTDSP1,
Protein Size: 1097

分子量

122 kDa

基因ID

5978

NCBI登录号

NM_005612, NP_005603

UniProt

Q13127

途径

Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity