SIRT7 抗体 (C-Term)
Quick Overview for SIRT7 抗体 (C-Term) (ABIN2779623)
抗原
See all SIRT7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- DVMRLLMAEL GLEIPAYSRW QDPIFSLATP LRAGEEGSHS RKSLCRSREE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SIRT7. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT7
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 400 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SIRT7 (Sirtuin 7 (SIRT7))
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别名
- SIRT7
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背景
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SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.
Alias Symbols: SIR2L7
Protein Interaction Partner: DDB1, VPRBP, APP, NOL6, YTHDC2, DDX31, RBM15, ANAPC1, NSD1, NOC3L, UBE2O, RBM25, CCAR2, CHD8, BEND3, PHRF1, DHX37, NUFIP2, CGN, XPO5, LRRC47, BIRC6, WDR18, THOC2, NUP107, REXO4, DDX24, XAB2, UGGT1, ZC3HAV1, YLPM1, NKRF, CCT5, SNW1, DHX30, DIS3, PUF60, COP
Protein Size: 400 -
分子量
- 45 kDa
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基因ID
- 51547
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NCBI登录号
- NM_016538, NP_057622
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UniProt
- Q9NRC8
抗原
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