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SIRT3 抗体 (C-Term)

SIRT3 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779610
发货至: 中国
  • 抗原 See all SIRT3 抗体
    SIRT3 (Sirtuin 3 (SIRT3))
    抗原表位
    • 16
    • 10
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 95
    • 43
    • 18
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow
    宿主
    • 86
    • 15
    • 2
    • 2
    • 2
    克隆类型
    • 93
    • 15
    多克隆
    标记
    • 59
    • 15
    • 12
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRT3 antibody is un-conjugated
    应用范围
    • 95
    • 64
    • 42
    • 10
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    VGPLAWHPRS RDVAQLGDVV HGVESLVELL GWTEEMRDLV QRETGKLDGP
    预测反应
    Cow: 100%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against SIRT3. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT3
    Top Product
    Discover our top product SIRT3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 257 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Vidimar, Gius, Chakravarti, Bulun, Wei, Kim: "Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." in: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).

    Marfè, Tafani, Fiorito, Pagnini, Iovane, De Martino: "Involvement of FOXO transcription factors, TRAIL-FasL/Fas, and sirtuin proteins family in canine coronavirus type II-induced apoptosis." in: PLoS ONE, Vol. 6, Issue 11, pp. e27313, (2011) (PubMed).

    Lanza, Short, Short, Raghavakaimal, Basu, Joyner, McConnell, Nair: "Endurance exercise as a countermeasure for aging." in: Diabetes, Vol. 57, Issue 11, pp. 2933-42, (2008) (PubMed).

  • 抗原
    SIRT3 (Sirtuin 3 (SIRT3))
    别名
    SIRT3 (SIRT3 产品)
    别名
    zgc:158774 antibody, sirtuin antibody, SIR2L3 antibody, 2310003L23Rik antibody, AI848213 antibody, Sir2l3 antibody, sirtuin 3 antibody, sirt3 antibody, SIRT3 antibody, Sirt3 antibody
    背景
    The SIRT3 gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT3 encodes a protein that is included in class I of the sirtuin family.
    Alias Symbols: SIR2L3
    Protein Interaction Partner: SIRT5, SKP2, UBC, HSPD1, CMYA5, PGAP1, RIF1, NCAPD2, HERC2, TTF2, UQCRH, UGDH, HSP90B1, SNTB1, SBF1, HSPA9, HSPA5, HSPA4, HSPA1L, GRN, ATP5B, ATP5A1, SIRT4, tat, XRCC6, FOXO3, DNM1L, PEX5,
    Protein Size: 257
    分子量
    28 kDa
    基因ID
    23410
    NCBI登录号
    NM_001017524, NP_001017524
    UniProt
    Q9NTG7
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