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SIRT3 抗体 (C-Term)

This anti-SIRT3 antibody is a 兔 多克隆 antibody detecting SIRT3 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 马 和 Cow. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2779610
发货至: 中国

Quick Overview for SIRT3 抗体 (C-Term) (ABIN2779610)

抗原

See all SIRT3 抗体
SIRT3 (Sirtuin 3 (SIRT3))

适用

  • 96
  • 43
  • 22
  • 9
  • 4
  • 4
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  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 马, Cow

宿主

  • 85
  • 23
  • 2
  • 2
  • 2

克隆类型

  • 91
  • 24
多克隆

标记

  • 72
  • 15
  • 11
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT3 antibody is un-conjugated

应用范围

  • 102
  • 55
  • 51
  • 21
  • 20
  • 11
  • 9
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 10
    • 8
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    VGPLAWHPRS RDVAQLGDVV HGVESLVELL GWTEEMRDLV QRETGKLDGP

    预测反应

    Cow: 100%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against SIRT3. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 257 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Vidimar, Gius, Chakravarti, Bulun, Wei, Kim: "Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." in: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).

    Marfè, Tafani, Fiorito, Pagnini, Iovane, De Martino: "Involvement of FOXO transcription factors, TRAIL-FasL/Fas, and sirtuin proteins family in canine coronavirus type II-induced apoptosis." in: PLoS ONE, Vol. 6, Issue 11, pp. e27313, (2011) (PubMed).

    Lanza, Short, Short, Raghavakaimal, Basu, Joyner, McConnell, Nair: "Endurance exercise as a countermeasure for aging." in: Diabetes, Vol. 57, Issue 11, pp. 2933-42, (2008) (PubMed).

  • 抗原

    SIRT3 (Sirtuin 3 (SIRT3))

    别名

    SIRT3

    背景

    The SIRT3 gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT3 encodes a protein that is included in class I of the sirtuin family.
    Alias Symbols: SIR2L3
    Protein Interaction Partner: SIRT5, SKP2, UBC, HSPD1, CMYA5, PGAP1, RIF1, NCAPD2, HERC2, TTF2, UQCRH, UGDH, HSP90B1, SNTB1, SBF1, HSPA9, HSPA5, HSPA4, HSPA1L, GRN, ATP5B, ATP5A1, SIRT4, tat, XRCC6, FOXO3, DNM1L, PEX5,
    Protein Size: 257

    分子量

    28 kDa

    基因ID

    23410

    NCBI登录号

    NM_001017524, NP_001017524

    UniProt

    Q9NTG7
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