SIRT3 抗体 (C-Term)
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- 抗原 See all SIRT3 抗体
- SIRT3 (Sirtuin 3 (SIRT3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIRT3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- VGPLAWHPRS RDVAQLGDVV HGVESLVELL GWTEEMRDLV QRETGKLDGP
- 预测反应
- Cow: 100%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against SIRT3. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT3
- Top Product
- Discover our top product SIRT3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 257 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." in: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).
: "Involvement of FOXO transcription factors, TRAIL-FasL/Fas, and sirtuin proteins family in canine coronavirus type II-induced apoptosis." in: PLoS ONE, Vol. 6, Issue 11, pp. e27313, (2011) (PubMed).
: "Endurance exercise as a countermeasure for aging." in: Diabetes, Vol. 57, Issue 11, pp. 2933-42, (2008) (PubMed).
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Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." in: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).
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- 抗原
- SIRT3 (Sirtuin 3 (SIRT3))
- 别名
- SIRT3 (SIRT3 产品)
- 背景
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The SIRT3 gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT3 encodes a protein that is included in class I of the sirtuin family.
Alias Symbols: SIR2L3
Protein Interaction Partner: SIRT5, SKP2, UBC, HSPD1, CMYA5, PGAP1, RIF1, NCAPD2, HERC2, TTF2, UQCRH, UGDH, HSP90B1, SNTB1, SBF1, HSPA9, HSPA5, HSPA4, HSPA1L, GRN, ATP5B, ATP5A1, SIRT4, tat, XRCC6, FOXO3, DNM1L, PEX5,
Protein Size: 257 - 分子量
- 28 kDa
- 基因ID
- 23410
- NCBI登录号
- NM_001017524, NP_001017524
- UniProt
- Q9NTG7
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