ISL1 抗体 (N-Term)
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- 抗原 See all ISL1 抗体
- ISL1 (ISL LIM Homeobox 1 (ISL1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 兔, 马, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ISL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IECFRCVACS RQLIPGDEFA LREDGLFCRA DHDVVERASL GAGDPLSPLH
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against ISL1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ISL1
- Top Product
- Discover our top product ISL1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 349 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ISL1 (ISL LIM Homeobox 1 (ISL1))
- 别名
- ISL1 (ISL1 产品)
- 别名
- Xisl-1 antibody, Xislet-1 antibody, islet1 antibody, ISLET-1 antibody, ISLET1 antibody, Isl-1 antibody, islet-1 antibody, isl-1=homeobox antibody, Islet-1 antibody, ISL LIM homeobox 1 S homeolog antibody, ISL LIM homeobox 1 antibody, ISL1 transcription factor, LIM/homeodomain antibody, isl1.S antibody, ISL1 antibody, Isl1 antibody, isl1 antibody
- 背景
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ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Isl-1, ISLET1
Protein Interaction Partner: ZNF511, KDM1A, RELA, SMAD3, CDKN2B, CDK6, APP, COPS5, SSBP4, LHX4, LDB2, ISL2, PECR, LDB1, LHX1, LHX3, LMX1A, RLIM, LMO2, ESR1, NR2F1, ISL1,
Protein Size: 349 - 分子量
- 39 kDa
- 基因ID
- 3670
- NCBI登录号
- NM_002202, NP_002193
- UniProt
- P61371
- 途径
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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