EYA3 抗体 (N-Term)
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北京 101111
Quick Overview for EYA3 抗体 (N-Term) (ABIN2779570)
抗原
See all EYA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- EYA3 Antibody - N-terminal region
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序列
- KMQESGEQTI SQVSNPDVSD QKPETSSLAS NLPMSEEIMT CTDYIPRSSN
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against EYA3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of human EYA3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32330-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- EYA3 (Eyes Absent Homolog 3 (EYA3))
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别名
- EYA3
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背景
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Background Information: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.
Gene Name: EYA transcriptional coactivator and phosphatase 3
Protein Name: eyes absent homolog 3
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分子量
- 39kDa
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基因ID
- 2140
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NCBI登录号
- NP_001269489
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UniProt
- Q99504
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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