BMP7 抗体 (N-Term)
(8 references)Quick Overview for BMP7 抗体 (N-Term) (ABIN2779569)
抗原
See all BMP7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QGKHNSAPMF MLDLYNAMAV EEGGGPGGQG FSYPYKAVFS TQGPPLASLQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 91%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 82%
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产品特性
- This is a rabbit polyclonal antibody against BMP7. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human BMP7
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anti-Bone Morphogenetic Protein 7 (BMP7) (AA 1-431) antibody
BMP7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal M1-F8 unconjugated
anti-Bone Morphogenetic Protein 7 (BMP7) (AA 132-431) antibodyBMP7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 7 (BMP7) (AA 239-431) antibodyBMP7 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6E5D12 unconjugated
anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibodyBMP7 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 7 (BMP7) (AA 293-350) antibodyBMP7 适用: 小鼠, 大鼠, 犬, 兔 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 7 (BMP7) (AA 293-431) antibodyBMP7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 7 (BMP7) (AA 15-44) antibodyBMP7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 7 (BMP7) (AA 280-309) antibodyBMP7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 7 (BMP7) (AA 123-393) antibodyBMP7 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 7 (BMP7) (AA 280-309), (C-Term) antibodyBMP7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33890 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 431 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Putative prognostic epithelial-to-mesenchymal transition biomarkers for aggressive prostate cancer." in: Experimental and molecular pathology, Vol. 95, Issue 2, pp. 220-6, (2013) (PubMed).
: "Effects of demineralized bone matrix on tendon-bone healing in an intra-articular rodent model." in: The American journal of sports medicine, Vol. 40, Issue 10, pp. 2365-74, (2012) (PubMed).
: "Expression of chondro-osteogenic BMPs in clinical samples of patellar tendinopathy." in: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, Vol. 20, Issue 7, pp. 1409-17, (2012) (PubMed).
: "Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma." in: Oncogene, Vol. 30, Issue 25, pp. 2823-35, (2011) (PubMed).
: "Elastomeric osteoconductive synthetic scaffolds with acquired osteoinductivity expedite the repair of critical femoral defects in rats." in: Tissue engineering. Part A, Vol. 17, Issue 3-4, pp. 503-11, (2011) (PubMed).
: "Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells." in: Biochemical and biophysical research communications, Vol. 393, Issue 4, pp. 877-82, (2010) (PubMed).
: "Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17811-20, (2010) (PubMed).
: "Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 2, pp. 192-205, (2010) (PubMed).
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: "Putative prognostic epithelial-to-mesenchymal transition biomarkers for aggressive prostate cancer." in: Experimental and molecular pathology, Vol. 95, Issue 2, pp. 220-6, (2013) (PubMed).
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- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
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别名
- BMP7
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背景
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The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
Alias Symbols: OP-1
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-7, MTUS2, TRIM27, KRTAP5-9, ACTN4, BMPR2, UBC, SMAD3, SOSTDC1, CHRDL2, GDF7, BMPR1B, NOG, ACVR2B, NCOA3, BMPR1A, ENG, ACVR2A, ACVR1, SMAD1, BMP7,
Protein Size: 431 -
分子量
- 49 kDa
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基因ID
- 655
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NCBI登录号
- NM_001719, NP_001710
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UniProt
- P18075
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途径
- Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
抗原
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