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HNF1B 抗体 (N-Term)

The 兔 多克隆 anti-HNF1B antibody is suitable to detect HNF1B in samples from 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马 和 豚鼠. It has been validated for WB.
产品编号 ABIN182534
发货至: 中国
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Quick Overview for HNF1B 抗体 (N-Term) (ABIN182534)

抗原

See all HNF1B 抗体
HNF1B (HNF1 Homeobox B (HNF1B))

适用

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人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 豚鼠

宿主

  • 44
  • 10
  • 1

克隆类型

  • 44
  • 10
  • 1
多克隆

标记

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This HNF1B antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 8
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    • 1
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    • 1
    N-Term

    序列

    LETLPLSPGS GAEPDTKPVF HTLTNGHAKG RLSGDEGSED GDDYDTPPIL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against HNF1B. It was validated on Western Blot.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1B
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 399 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HNF1B (HNF1 Homeobox B (HNF1B))

    别名

    HNF1B

    背景

    Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.
    Alias Symbols: FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
    Protein Interaction Partner: HIST1H3A, PCBD1, CREBBP, HNF1A, ATF1, CREB1,
    Protein Size: 399

    分子量

    45 kDa

    基因ID

    6928

    NCBI登录号

    NM_006481, NP_006472

    途径

    Hormone Transport, Stem Cell Maintenance, Tube Formation
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