POU1F1 抗体 (Middle Region)
Quick Overview for POU1F1 抗体 (Middle Region) (ABIN2779561)
抗原
See all POU1F1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- KRRTTISIAA KDALERHFGE QNKPSSQEIM RMAEELNLEK EVVRVWFCNR
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against POU1F1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human POU1F1
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anti-POU Class 1 Homeobox 1 (POU1F1) (C-Term) antibody
POU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) (AA 75-124) antibodyPOU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) (C-Term) antibodyPOU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠, Pig, 斑马鱼, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) antibodyPOU1F1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) (N-Term) antibodyPOU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) (N-Term) antibodyPOU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 1 Homeobox 1 (POU1F1) antibodyPOU1F1 适用: 人, 犬 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 291 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
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别名
- POU1F1
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背景
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PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: GHF-1, PIT1, Pit-1, Pit-1 beta, CPHD1, POU1F1a
Protein Interaction Partner: CEBPD, NCOR1, CREBBP, MED1, GATA2, NR1I3, NR1I2, PITX1, JUN, ETS1, NR3C1, VDR, PPARG, PPARA,
Protein Size: 291 -
分子量
- 33 kDa
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基因ID
- 5449
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NCBI登录号
- NM_000306, NP_000297
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UniProt
- P28069
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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