ZUFSP 抗体 (Middle Region)
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北京 101111
Quick Overview for ZUFSP 抗体 (Middle Region) (ABIN2779538)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- ZUP1 Antibody - middle region
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序列
- RQEIEEFQKL QRQYGLDNSG GYKQQQLRNM EIEVNRGRMP PSEFHRRKAD
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预测反应
- Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against C6orf113. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human C6orf113
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32274-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ZUFSP (Zinc Finger with UFM1-Specific Peptidase Domain (ZUFSP))
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别名
- ZUP1
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背景
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Background Information: This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers.
Gene Name: zinc finger containing ubiquitin peptidase 1
Alternative Symbols: DUB, ZUFSP, C6orf113
Protein Name: zinc finger-containing ubiquitin peptidase 1
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分子量
- 66kDa
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基因ID
- 221302
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NCBI登录号
- NP_659499
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UniProt
- Q96AP4
抗原
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