ESRRA 抗体 (C-Term)
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北京 101111
Quick Overview for ESRRA 抗体 (C-Term) (ABIN2779529)
抗原
See all ESRRA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Esrra Antibody - C-terminal region
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序列
- AGRAGPGGGA ERRRAGRLLL TLPLLRQTAG KVLAHFYGVK LEGKVPMHKL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Esrra. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32259-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ESRRA (Estrogen-Related Receptor alpha (ESRRA))
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别名
- Esrra
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背景
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Background Information: Esrra binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. It can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. It binds to the C1 region of the lactoferrin gene promoter. It requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
Gene Name: Estrogen related receptor, alpha
Alternative Symbols: Er, Es, Nr3, Err1, Nr3b1, Estrra, ERRalpha
Protein Name: Steroid hormone receptor ERR1
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分子量
- 45kDa
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基因ID
- 26379
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NCBI登录号
- NP_031979
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UniProt
- O08580
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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