EGR1 抗体 (N-Term)
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北京 101111
Quick Overview for EGR1 抗体 (N-Term) (ABIN2779517)
抗原
See all EGR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DNYPKLEEMM LLSNGAPQFL GAAGAPEGSG SNSSSSSSGG GGGGGGGSNS
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预测反应
- Cow: 87%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against EGR1. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EGR1
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anti-Early Growth Response 1 (EGR1) (AA 444-543) antibody
EGR1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6E8 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 444-543) antibodyEGR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 9-37) antibodyEGR1 适用: 人, 小鼠 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 9-37), (N-Term) antibodyEGR1 适用: 人, 小鼠 WB, IF, FACS 宿主: 兔 Polyclonal RB19179 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 401-453) antibodyEGR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 282-433) antibodyEGR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 1-250) antibodyEGR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 444-543) antibodyEGR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 211-320) antibodyEGR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 444-544) antibodyEGR1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6E8 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 543 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153256, (2016) (PubMed).
: "Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 29, Issue 7, pp. 1627-38, (2014) (PubMed).
: "Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." in: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).
: "The enhancement of stress-related memory by glucocorticoids depends on synapsin-Ia/Ib." in: Molecular psychiatry, Vol. 15, Issue 12, pp. 1125, 1140-51, (2010) (PubMed).
: "Egr1 and Gas6 facilitate the adaptation of HEK-293 cells to serum-free media by conferring enhanced viability and higher growth rates." in: Biotechnology and bioengineering, Vol. 99, Issue 6, pp. 1443-52, (2008) (PubMed).
: "Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway." in: Biological chemistry, Vol. 388, Issue 5, pp. 489-95, (2007) (PubMed).
: "Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression." in: The Journal of biological chemistry, Vol. 282, Issue 7, pp. 4924-31, (2007) (PubMed).
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: "Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153256, (2016) (PubMed).
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- EGR1 (Early Growth Response 1 (EGR1))
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别名
- EGR1
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背景
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Early Growth Response Protein 1 (EGR1, Krox-24 protein, nerve growth factor-induced protein A, Transcription factor ETR103, Zinc finger protein 225) belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225
Protein Interaction Partner: CEBPB, WT1, SUMO1, TP53, MDM2, EP300, CDKN2A, SRA1, IL1B, PTEN, SP1, SNAI1, TBX2, PFDN5, SREBF2, ERBB3, NAB2, PITX1, NAB1, NFATC2, CREBBP, PSMA3, JUN, RELA, CSNK2A1, NFATC1, GADD45B, GADD45A,
Protein Size: 543 -
分子量
- 57 kDa
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基因ID
- 1958
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NCBI登录号
- NM_001964, NP_001955
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UniProt
- P18146
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途径
- Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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