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SPIC 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects SPIC in WB. It exhibits reactivity toward 人, 小鼠, Cow, 马, 犬, 豚鼠, 大鼠, 兔, Pig 和 斑马鱼.It has been mentioned in 1 publication
产品编号 ABIN2779513
发货至: 中国
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Quick Overview for SPIC 抗体 (C-Term) (ABIN2779513)

抗原

See all SPIC 抗体
SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

适用

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人, 小鼠, Cow, 马, 犬, 豚鼠, 大鼠, 兔, Pig, 斑马鱼

宿主

  • 34
  • 1

克隆类型

  • 34
  • 1
多克隆

标记

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This SPIC antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 6
    • 5
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    • 1
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    • 1
    C-Term

    序列

    EKLAELWGKR KGNRKTMTYQ KMARALRNYG RSGEITKIRR KLTYQFSEAI

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against SPIC. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 248 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zhu, Schweitzer, Romer, Sulentic, DeKoter: "Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling." in: European journal of immunology, Vol. 38, Issue 9, pp. 2587-99, (2008) (PubMed).

  • 抗原

    SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

    别名

    SPIC

    背景

    SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC Regulates VCAM1 gene expression.
    Alias Symbols: MGC40611, SPI-C
    Protein Interaction Partner: APP,
    Protein Size: 248

    分子量

    29 kDa

    基因ID

    121599

    NCBI登录号

    NM_152323, NP_689536

    UniProt

    Q8N5J4
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