ZFPM1 抗体 (Middle Region)
(1 reference)Quick Overview for ZFPM1 抗体 (Middle Region) (ABIN2779499)
抗原
See all ZFPM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PPPPPPGHAP APESPRPGSG SGSGPGLAPA RSPGPAADGP IDLSKKPRRP
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预测反应
- Cow: 91%, Human: 100%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against ZFPM1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ZFPM1
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anti-Zinc Finger Protein, Multitype 1 (ZFPM1) antibody
ZFPM1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, Multitype 1 (ZFPM1) (AA 954-987), (C-Term) antibodyZFPM1 适用: 人 WB 宿主: 兔 Polyclonal RB51246 unconjugated
anti-Zinc Finger Protein, Multitype 1 (ZFPM1) (AA 86-195) antibodyZFPM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein, Multitype 1 (ZFPM1) (AA 755-804) antibodyZFPM1 适用: 人, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, Multitype 1 (ZFPM1) (AA 935-984) antibodyZFPM1 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein, Multitype 1 (ZFPM1) (N-Term) antibodyZFPM1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1006 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Differential context-dependent effects of friend of GATA-1 (FOG-1) on mast-cell development and differentiation." in: Blood, Vol. 111, Issue 4, pp. 1924-32, (2008) (PubMed).
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: "Differential context-dependent effects of friend of GATA-1 (FOG-1) on mast-cell development and differentiation." in: Blood, Vol. 111, Issue 4, pp. 1924-32, (2008) (PubMed).
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- ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))
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别名
- ZFPM1
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背景
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ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.
Alias Symbols: FOG, FOG1, ZNF408, ZNF89A
Protein Interaction Partner: GSK3B, CTBP2, TRIM21, MTA1, RBBP4, Rb1, GATA1, GIPC1, TOP3B, GATA2,
Protein Size: 1006 -
分子量
- 105 kDa
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基因ID
- 161882
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NCBI登录号
- NM_153813, NP_722520
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UniProt
- Q8IX07
抗原
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