MYCN 抗体 (C-Term)
Quick Overview for MYCN 抗体 (C-Term) (ABIN2779428)
抗原
See all MYCN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- EDAPPQKKIK SEASPRPLKS VIPPKAKSLS PRNSDSEDSE RRRNHNILER
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 77%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against MYCN. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 464 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
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别名
- MYCN
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背景
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MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas
Alias Symbols: NMYC, ODED, MODED, N-myc, bHLHe37
Protein Interaction Partner: TRIM32, UBC, HDAC5, NMI, MAX, CDKN2A, GRK5, ZBTB17, SIRT1, YEATS4, CSNK1E, FBXW7, PIAS2, AURKA, SP1, NTRK1, NGFR, HDAC2, CSNK2A1, YAF2, MXD1, CSNK2A2, SLC1A2,
Protein Size: 464 -
分子量
- 50 kDa
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基因ID
- 4613
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NCBI登录号
- NM_005378, NP_005369
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UniProt
- P04198
抗原
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