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MYCN 抗体 (C-Term)

The 兔 多克隆 anti-MYCN antibody (ABIN2779428) specifically detects MYCN in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 马, Pig 和 兔 samples.
产品编号 ABIN2779428
发货至: 中国
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Quick Overview for MYCN 抗体 (C-Term) (ABIN2779428)

抗原

See all MYCN 抗体
MYCN (N-Myc Proto-Oncogene Protein (MYCN))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, Pig, 兔

宿主

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  • 18

克隆类型

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多克隆

标记

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This MYCN antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    EDAPPQKKIK SEASPRPLKS VIPPKAKSLS PRNSDSEDSE RRRNHNILER

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 77%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against MYCN. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 464 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MYCN (N-Myc Proto-Oncogene Protein (MYCN))

    别名

    MYCN

    背景

    MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas
    Alias Symbols: NMYC, ODED, MODED, N-myc, bHLHe37
    Protein Interaction Partner: TRIM32, UBC, HDAC5, NMI, MAX, CDKN2A, GRK5, ZBTB17, SIRT1, YEATS4, CSNK1E, FBXW7, PIAS2, AURKA, SP1, NTRK1, NGFR, HDAC2, CSNK2A1, YAF2, MXD1, CSNK2A2, SLC1A2,
    Protein Size: 464

    分子量

    50 kDa

    基因ID

    4613

    NCBI登录号

    NM_005378, NP_005369

    UniProt

    P04198
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