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ASCL2 抗体 (Middle Region)

This anti-ASCL2 antibody is a 兔 多克隆 antibody detecting ASCL2 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2779425
发货至: 中国

Quick Overview for ASCL2 抗体 (Middle Region) (ABIN2779425)

抗原

See all ASCL2 抗体
ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼

宿主

  • 32
  • 4
  • 1

克隆类型

  • 32
  • 5
多克隆

标记

  • 24
  • 2
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  • 1
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This ASCL2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 11
    • 7
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    • 1
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    Middle Region

    序列

    QALRQHVPHG GASKKLSKVE TLRSAVEYIR ALQRLLAEHD AVRNALAGGL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 100%, Zebrafish: 77%

    产品特性

    This is a rabbit polyclonal antibody against ASCL2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ASCL2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 193 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Schwitalla, Fingerle, Cammareri, Nebelsiek, Göktuna, Ziegler, Canli, Heijmans, Huels, Moreaux, Rupec, Gerhard, Schmid, Barker, Clevers, Lang, Neumann, Kirchner, Taketo, van den Brink, Sansom, Arkan et al.: "Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. ..." in: Cell, Vol. 152, Issue 1-2, pp. 25-38, (2013) (PubMed).

  • 抗原

    ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

    别名

    ASCL2

    背景

    AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1649 BC028140.1 1-1649 1650-1864 BC057801.1 1286-1500
    Alias Symbols: ASH2, HASH2, MASH2, bHLHa45
    Protein Interaction Partner: EP300, APEX1, CALM3, CALM1, HCFC1, TUBB, KMT2C, NCOA6, TUBA4A, RBBP5,
    Protein Size: 193

    分子量

    20 kDa

    基因ID

    430

    NCBI登录号

    NM_005170, NP_005161

    UniProt

    Q99929

    途径

    Stem Cell Maintenance
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