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LMX1A 抗体 (Middle Region)

LMX1A 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779408
发货至: 中国
  • 抗原 See all LMX1A 抗体
    LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
    抗原表位
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 24
    • 18
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔
    宿主
    • 27
    克隆类型
    • 27
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    This LMX1A antibody is un-conjugated
    应用范围
    • 22
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    QNQRAKMKKL ARRQQQQQQD QQNTQRLSSA QTNGGGSAGM EGIMNPYTAL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against LMX1A. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human LMX1A
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 382 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
    别名
    LMX1A (LMX1A 产品)
    别名
    Lmx1.1 antibody, dr antibody, dreher antibody, sst antibody, LMX1 antibody, LMX1.1 antibody, si:ch211-260g14.3 antibody, LIM homeobox transcription factor 1 alpha antibody, LIM homeobox transcription factor 1, alpha antibody, Lmx1a antibody, LMX1A antibody, lmx1a antibody
    背景
    Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin. Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-199 AL160058.8 14249-14447 c 200-2447 AK127724.1 362-2609 2448-3382 AL390730.12 9415-10349 c
    Alias Symbols: LMX-1, LMX1, LMX1.1, MGC87616
    Protein Interaction Partner: LDB1, BMPR2, ISL1, LHX3, LMX1A, TCF3,
    Protein Size: 382
    分子量
    43 kDa
    基因ID
    4009
    NCBI登录号
    NM_177398, NP_796372
    UniProt
    Q8TE12
    途径
    Dopaminergic Neurogenesis
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