TRIM23 抗体 (N-Term)
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北京 101111
Quick Overview for TRIM23 抗体 (N-Term) (ABIN2779407)
抗原
See all TRIM23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- TRIM23 Antibody - N-terminal region
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序列
- CPFDRQVTDL GDSGVWGLKK NFALLELLER LQNGPIGQYG AAEESIGISG
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预测反应
- Cow: 90%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Rabbit: 85%, Rat: 91%
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产品特性
- This is a rabbit polyclonal antibody against TRIM23. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM23
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31998-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TRIM23 (Tripartite Motif Containing 23 (TRIM23))
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别名
- TRIM23
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背景
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Background Information: TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Gene Name: Tripartite motif containing 23
Alternative Symbols: ARD1, ARFD1, RNF46
Protein Name: E3 ubiquitin-protein ligase TRIM23
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分子量
- 64kDa
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基因ID
- 373
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NCBI登录号
- NP_001647
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UniProt
- P36406
抗原
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