PDX1 抗体 (N-Term)
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北京 101111
Quick Overview for PDX1 抗体 (N-Term) (ABIN2779403)
抗原
See all PDX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Pdx1 Antibody - N-terminal region
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序列
- LYMGRQPPPP PPPQFTSSLG SLEQGSPPDI SPYEVPPLAS DDPAGAHLHH
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Pdx1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31991-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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别名
- Pdx1
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背景
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Background Information: Pdx1 activates insulin and somatostatin gene transcription. It is a key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. It binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
Gene Name: Pancreatic and duodenal homeobox 1
Alternative Symbols: Ip, IPF, IDX-, Ipf1, Mody, STF-, pdx-, IDX-1, IPF-1, Mody4, STF-1, pdx-1
Protein Name: Pancreas/duodenum homeobox protein 1
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分子量
- 31kDa
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基因ID
- 18609
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NCBI登录号
- NP_032840
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UniProt
- P52946
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途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
抗原
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