NK2 Homeobox 5 抗体 (N-Term)
Quick Overview for NK2 Homeobox 5 抗体 (N-Term) (ABIN2779388)
抗原
See all NK2 Homeobox 5 (NKX2-5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- ELGRAPSPAK CASAFPAAPA FYPRAYSDPD PAKDPRAEKK ELCALQKAVE
-
预测反应
- Cow: 85%, Dog: 85%, Guinea Pig: 92%, Horse: 77%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 92%
-
产品特性
- This is a rabbit polyclonal antibody against NKX2-5. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the n terminal region of human Nkx2-5
-
-
anti-NK2 Homeobox 5 (NKX2-5) (Internal Region) antibody
Verified NKX2-5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-324) antibodyNKX2-5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4-G5 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 98-133) antibodyNKX2-5 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB52360 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 192-225) antibodyNKX2-5 适用: 小鼠, 大鼠, Hamster WB 宿主: 兔 Polyclonal RB51144 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) antibodyNKX2-5 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-130) antibodyNKX2-5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-130) antibodyNKX2-5 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-130) antibodyNKX2-5 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C1 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 300-324) antibodyNKX2-5 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 5 (NKX2-5) antibodyNKX2-5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2E1 unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 324 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- NK2 Homeobox 5 (NKX2-5)
-
别名
- Nkx2-5
-
背景
-
Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1211 U34962.1 1-1211 1212-1585 BC025711.1 1143-1516
Alias Symbols: CSX, CSX1, NKX2.5, NKX2E, NKX4-1, VSD3, CHNG5, HLHS2
Protein Interaction Partner: JARID2, GATA4, KDM6A, SMAD4, CAMTA2, TLE1, HDAC1, ID3, ID2, ID1, HIPK1, HIPK2, FOXH1, TBX5, TBX2, SRF, CSNK2A1,
Protein Size: 324 -
分子量
- 35 kDa
-
基因ID
- 1482
-
NCBI登录号
- NM_004387, NP_004378
-
UniProt
- P52952
-
途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
-
