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NK2 Homeobox 5 抗体 (N-Term)

This anti-NK2 Homeobox 5 antibody is a 兔 多克隆 antibody detecting NK2 Homeobox 5 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔 和 马.
产品编号 ABIN2779388
发货至: 中国

Quick Overview for NK2 Homeobox 5 抗体 (N-Term) (ABIN2779388)

抗原

See all NK2 Homeobox 5 (NKX2-5) 抗体
NK2 Homeobox 5 (NKX2-5)

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马

宿主

  • 42
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克隆类型

  • 44
  • 7
多克隆

标记

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This NK2 Homeobox 5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    ELGRAPSPAK CASAFPAAPA FYPRAYSDPD PAKDPRAEKK ELCALQKAVE

    预测反应

    Cow: 85%, Dog: 85%, Guinea Pig: 92%, Horse: 77%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against NKX2-5. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the n terminal region of human Nkx2-5
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 324 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NK2 Homeobox 5 (NKX2-5)

    别名

    Nkx2-5

    背景

    Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1211 U34962.1 1-1211 1212-1585 BC025711.1 1143-1516
    Alias Symbols: CSX, CSX1, NKX2.5, NKX2E, NKX4-1, VSD3, CHNG5, HLHS2
    Protein Interaction Partner: JARID2, GATA4, KDM6A, SMAD4, CAMTA2, TLE1, HDAC1, ID3, ID2, ID1, HIPK1, HIPK2, FOXH1, TBX5, TBX2, SRF, CSNK2A1,
    Protein Size: 324

    分子量

    35 kDa

    基因ID

    1482

    NCBI登录号

    NM_004387, NP_004378

    UniProt

    P52952

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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