DYRK3 抗体 (N-Term)
(1 reference)Quick Overview for DYRK3 抗体 (N-Term) (ABIN2779364)
抗原
See all DYRK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GDHTQHFLDG GEMKVEQLFQ EFGNRKSNTI QSDGISDSEK CSPTVSQGKS
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预测反应
- Human: 100%, Mouse: 86%
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产品特性
- This is a rabbit polyclonal antibody against DYRK3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DYRK3
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anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (AA 1-568) antibody
DYRK3 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) antibodyDYRK3 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) antibodyDYRK3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (AA 1-300) antibodyDYRK3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (AA 1-569) antibodyDYRK3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (AA 71-120) antibodyDYRK3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (AA 35-84) antibodyDYRK3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 588 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling." in: Cell, Vol. 152, Issue 4, pp. 791-805, (2013) (PubMed).
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: "Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling." in: Cell, Vol. 152, Issue 4, pp. 791-805, (2013) (PubMed).
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- DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))
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别名
- DYRK3
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背景
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This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DYRK5, RED, REDK, hYAK3-2
Protein Interaction Partner: DYRK3, SORL1, FBXO25, PRNP, NEDD4L,
Protein Size: 588 -
分子量
- 66 kDa
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基因ID
- 8444
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NCBI登录号
- NM_003582, NP_003573
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UniProt
- O43781
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途径
- Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
抗原
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