HAND2 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for HAND2 抗体 (C-Term) (ABIN2779346)
抗原
See all HAND2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Hand2 Antibody - C-terminal region
-
序列
- DQNGEAEAFK AEIKKTDVKE EKRKKELNEI LKSTVSSNDK KTKGRTGWPQ
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 87%
-
产品特性
- This is a rabbit polyclonal antibody against Hand2. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30571-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
-
别名
- Hand2
-
背景
-
Background Information: Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck.
Gene Name: Heart and neural crest derivatives expressed transcript 2
Alternative Symbols: Hed, Th2, dHA, Ehan, Thin, bHLHa, dHAND, Ehand2, Thing2, bHLHa26, AI225906, AI661148
Protein Name: Heart- and neural crest derivatives-expressed protein 2
-
分子量
- 24kDa
-
基因ID
- 15111
-
NCBI登录号
- NP_034532
-
UniProt
- Q61039
-
途径
- Tube Formation, Feeding Behaviour
抗原
-