HAND2 抗体 (C-Term)
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- 抗原 See all HAND2 抗体
- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 马, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HAND2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DQNGEAEAFK AEIKKTDVKE EKRKKELNEI LKSTVSSNDK KTKGRTGWPQ
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 87%
- 产品特性
- This is a rabbit polyclonal antibody against Hand2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product HAND2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 217 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
- 别名
- Hand2 (HAND2 产品)
- 背景
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Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck.
Alias Symbols: AI225906, AI661148, Ehand2, Hed, Th2, Thing2, bHLHa26, dHAND
Protein Interaction Partner: Nkx2-5, Hand1, Tcf3, Tcf4, Tcf12, Hoxd13, Twist1,
Protein Size: 217 - 分子量
- 24 kDa
- 基因ID
- 15111
- NCBI登录号
- NM_010402, NP_034532
- UniProt
- Q61039
- 途径
- Tube Formation, Feeding Behaviour
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