RAD17 抗体 (N-Term)
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- 抗原 See all RAD17 抗体
- RAD17
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抗原表位
- N-Term
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适用
- 人, 大鼠, 犬, Cow, Pig, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAD17 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MNQVTDWVDP SFDDFLECSG VSTITATSLG VNNSSHRRKN GPSTLESSRF
- 预测反应
- Cow: 89%, Dog: 100%, Horse: 92%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 89%
- 产品特性
- This is a rabbit polyclonal antibody against RAD17. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RAD17
- Top Product
- Discover our top product RAD17 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 670 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RAD17
- 别名
- RAD17 (RAD17 产品)
- 别名
- zgc:91969 antibody, RAD17 antibody, K2A18.21 antibody, K2A18_21 antibody, RADIATION SENSITIVE 17 antibody, CCYC antibody, HRAD17 antibody, R24L antibody, RAD17SP antibody, RAD24 antibody, 9430035O09Rik antibody, MmRad24 antibody, RAD17 checkpoint clamp loader component antibody, Rad17p antibody, RADIATION SENSITIVE 17 antibody, RAD17 antibody, rad17 antibody, ATRAD17 antibody, Rad17 antibody
- 背景
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RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation.
Alias Symbols: CCYC, FLJ41520, HRAD17, R24L, RAD17SP, RAD24
Protein Interaction Partner: USP20, UBC, PRMT6, CBX7, CBX6, RAD9A, CDH1, ATR, RFC1, H2AFX, FOXO3, ATM, CLSPN, ALK, RAD9B, POLE, HUS1, RAD1, NHP2L1, MCM7, RFC4, RFC5, RFC3, RFC2, POLE4, POLE3, POLE2, PRKDC,
Protein Size: 670 - 分子量
- 76 kDa
- 基因ID
- 5884
- NCBI登录号
- NM_002873, NP_002864
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