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TYK2 抗体 (C-Term)

TYK2 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779322
发货至: 中国
  • 抗原 See all TYK2 抗体
    TYK2 (Tyrosine Kinase 2 (TYK2))
    抗原表位
    • 19
    • 16
    • 15
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, 马, 犬, 豚鼠, Cow
    宿主
    • 72
    • 5
    克隆类型
    • 72
    • 6
    多克隆
    标记
    • 35
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TYK2 antibody is un-conjugated
    应用范围
    • 61
    • 38
    • 20
    • 13
    • 13
    • 13
    • 10
    • 6
    • 4
    • 2
    • 2
    Western Blotting (WB)
    序列
    HRDLAARNVL LDNDRLVKIG DFGLAKAVPE GHEYYRVRED GDSPVFWYAP
    预测反应
    Cow: 91%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against TYK2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human TYK2
    Top Product
    Discover our top product TYK2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1187 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TYK2 (Tyrosine Kinase 2 (TYK2))
    别名
    TYK2 (TYK2 产品)
    别名
    JTK1 antibody, tyrosine kinase 2 antibody, TYK2 antibody, Tyk2 antibody
    背景
    This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
    Alias Symbols: JTK1
    Protein Interaction Partner: KHDRBS2, KRT40, TRAF4, HNRNPK, FHL3, COPS5, JAK3, UBC, HSP90AA1, TYK2, PTAFR, EIF2AK2, LNX1, KLF10, SOCS1, TK1, DNM2, IFNAR1, JAKMIP1, XRCC5, STAM2, PRMT5, IFNAR2, CRKL, GHR, IRS2, IL6ST, STAT2, STAT1, IL13RA1, GNB2L1, PTPN1, PTPN6, PDGFRB, PLAUR, PIK3R1,
    Protein Size: 1187
    分子量
    134 kDa
    基因ID
    7297
    NCBI登录号
    NM_003331, NP_003322
    UniProt
    P29597
    途径
    JAK/STAT Signaling, Hepatitis C
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