TYK2 抗体 (C-Term)
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北京 101111
Quick Overview for TYK2 抗体 (C-Term) (ABIN2779322)
抗原
See all TYK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- TYK2 Antibody - C-terminal region
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序列
- HRDLAARNVL LDNDRLVKIG DFGLAKAVPE GHEYYRVRED GDSPVFWYAP
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预测反应
- Cow: 91%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against TYK2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TYK2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30319-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TYK2 (Tyrosine Kinase 2 (TYK2))
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别名
- TYK2
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背景
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Background Information: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Gene Name: Tyrosine kinase 2
Alternative Symbols: JTK1, IMD35
Protein Name: Non-receptor tyrosine-protein kinase TYK2
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分子量
- 134kDa
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基因ID
- 7297
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NCBI登录号
- NP_003322
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UniProt
- P29597
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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