PDPK1 抗体 (Middle Region)
Quick Overview for PDPK1 抗体 (Middle Region) (ABIN2779320)
抗原
See all PDPK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IIHRDLKPEN ILLNEDMHIQ ITDFGTAKVL SPESKQARAN SFVGTAQYVS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against PDPK1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PDPK1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 556 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
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别名
- PDPK1
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背景
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PDPK1 phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. It may play a general role in signaling processes and in development.
Alias Symbols: MGC20087, MGC35290, PDK1, PRO0461, PkB-like, PkB-like 1
Protein Interaction Partner: SRPK1, AKT1, APP, YWHAQ, STRAP, SGK1, UBC, SOCS3, PEA15, TCAP, ZNF133, SMARCB1, SBF1, XRCC6, BLMH, FAM213B, CARD11, C2orf44, KATNBL1, PNO1, DDIT4, PHAX, LUC7L2, ZC3HC1, GIT1, POLDIP2, XPO7, PRKCQ, G3BP1, PA2G4, SND1, TBL2, RPS6KB2, RPS6KB1, CDAN1, AKTIP,
Protein Size: 556 -
分子量
- 63 kDa
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基因ID
- 5170
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NCBI登录号
- NM_002613, NP_002604
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UniProt
- O15530
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途径
- PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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