HSP90AA1 抗体 (N-Term)
Quick Overview for HSP90AA1 抗体 (N-Term) (ABIN2779296)
抗原
See all HSP90AA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- HLYKDLQPFI LLRLLMPEET QTQDQPMEEE EVETFAFQAE IAQLMSLIIN
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预测反应
- Cow: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%
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产品特性
- This is a rabbit polyclonal antibody against HSP90AA1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HSP90AA1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 854 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))
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别名
- HSP90AA1
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背景
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HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1, MIM 191175) and mitochondria (TRAP1, MIM 606219).
Alias Symbols: FLJ31884, HSP86, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, HSP89A
Protein Interaction Partner: AHSA1, STUB1, HUWE1, ISG15, RAF1, PTGDS, PTGDR, SIRT1, CDC37, STIP1, HSF1, HIF1A, NR3C1, UBC, PTGES3, FUS, CDC25C, CDK1, SUMO1, STK36, KEAP1, PSMD10, AURKA, SUMO2, SUMO3, MAP3K11, MDM2, LGALS3BP, CEP57, AURKB, CEP76, VHL, TUBG1, TP53, BRCA1, CEP250, AIP,
Protein Size: 854 -
分子量
- 98 kDa
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基因ID
- 3320
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NCBI登录号
- NM_001017963, NP_001017963
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UniProt
- P07900
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途径
- M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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