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Calreticulin 抗体 (C-Term)

CALR 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 马, 斑马鱼, Saccharomyces cerevisiae, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779285
发货至: 中国
  • 抗原 See all Calreticulin (CALR) 抗体
    Calreticulin (CALR)
    抗原表位
    • 16
    • 12
    • 7
    • 6
    • 6
    • 4
    • 4
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    C-Term
    适用
    • 121
    • 62
    • 49
    • 11
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    人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 马, 斑马鱼, Saccharomyces cerevisiae, 山羊
    宿主
    • 115
    • 9
    • 2
    • 1
    克隆类型
    • 108
    • 19
    多克隆
    标记
    • 66
    • 12
    • 11
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    • 1
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    This Calreticulin antibody is un-conjugated
    应用范围
    • 103
    • 54
    • 46
    • 38
    • 29
    • 26
    • 24
    • 17
    • 14
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    • 3
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    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    FGNETWGVTK AAEKQMKDKQ DEEQRLKEEE EDKKRKEEEE AEDKEDDEDK
    预测反应
    Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 92%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against CALR. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human CALR
    Top Product
    Discover our top product CALR Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 417 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Taguchi, Rho, Yan, Zhang, Zhao, Xu, Tripathi, Wang, Brenner, Kucherlapati, Kucherlapati, Boutin, Wang, DePinho, Feng, Lampe, Hanash: "MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas." in: Cancer prevention research (Philadelphia, Pa.), Vol. 8, Issue 11, pp. 1112-9, (2015) (PubMed).

  • 抗原
    Calreticulin (CALR)
    别名
    CALR (CALR 产品)
    别名
    CRT antibody, RO antibody, SSA antibody, cC1qR antibody, crc antibody, crt antibody, Calregulin antibody, CG9429 antibody, Clr antibody, Dmel\\CG9429 antibody, anon-EST:Liang-2.11 antibody, anon-EST:Liang-2.17 antibody, anon-EST:fe3D7 antibody, clone 2.11 antibody, clone 2.17 antibody, eth antibody, potp antibody, cc1qr antibody, ssa antibody, NV19007 antibody, CRP55 antibody, ERp60 antibody, HACBP antibody, CHOT1 antibody, CHT1 antibody, CT1 antibody, AA589632 antibody, CRTR antibody, Creat antibody, CCDS1 antibody, calrl2 antibody, fc66d10 antibody, wu:fc66d10 antibody, wu:fj50c03 antibody, zgc:66153 antibody, calreticulin antibody, calreticulin L homeolog antibody, Calreticulin antibody, putative calreticulin antibody, solute carrier family 6 member 8 antibody, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 antibody, CALR antibody, calr.L antibody, Crt antibody, crt antibody, CRT antibody, Calr antibody, calr antibody, LMJF_31_2600 antibody, Crc antibody, Slc6a8 antibody, SLC6A8 antibody, LOC8269812 antibody
    背景
    Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
    Alias Symbols: RO, CRT, SSA, cC1qR
    Protein Interaction Partner: HUWE1, UBC, LGR4, MDM2, RNF2, SUZ12, rev, AARSD1, THG1L, NSUN2, SH3GLB1, EEF2K, ARPC1A, ANP32B, ACTR2, ARPC1B, ARPC3, ARPC5, TPD52L2, SH3GL1, RPA3, RPA1, PRKACA, PFDN5, LPP, PARK2, UPF2, UBD, SOX2, PDIA3, CLN5, ITGA3, HLA-E, HLA-A, CALR, SLC27A2, env, MTN
    Protein Size: 417
    分子量
    48 kDa
    基因ID
    811
    NCBI登录号
    NM_004343, NP_004334
    UniProt
    P27797
    途径
    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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